69 randomised trials · 153,902 participants
Fractures and falls: the 2026 synthesis
Finding. Overall, the review found little or no clinically important benefit from calcium, vitamin D or combined supplementation for preventing fractures and falls. Calcium alone had a risk ratio of 0.91 for any fracture; the 95% confidence interval of 0.81–1.01 included no effect.
Interpretation & limitations. Most study populations lived independently and were not at high fracture risk. Evidence for high-risk groups was more limited. These findings neither replace correcting inadequate intake nor constitute osteoporosis treatment advice.
Study & original source [4] ↗